Searchable abstracts of presentations at key conferences in endocrinology

ea0099p302 | Endocrine-Related Cancer | ECE2024

Alteration in the molecular components of machinery that regulate gene expression mechanisms and genomic stability in thyroid cancer and their association with tumour behaviour and/or clinical features

Martinez Vara Andrea , Pastrana Francisco Porcel , Di-Caro Isidoro , Sarmento-Cabral Andre , Sanchez Sanchez Rafael , Lluch Ana Romero , Santisteban Pilar , Gonzalez Elena Navarro , Moreno Maria A Gavez , Luque Raul M , Fuentes Antonio J Martinez

Emerging evidence indicates that the cellular machineries controlling gene expression mechanisms and genomic stability are altered in several endocrine-related cancers (ERCs), leading to some oncogenic events associated with tumour progression/aggressiveness. However, whether this phenomenon also occurs in thyroid cancer has not been yet explored. Therefore, this study was focused on: 1) investigating the potential alteration in the levels of components of the molecular machin...